SYSTAG turnkey solutions for automated laboratory reactors and workstations.

SYSTAG provides specialist turnkey solutions for automated laboratory reactors and parallel synthesis workstations, which focus on process optimisation from grams to kilograms for the pharmaceutical industry.

Parallel synthesis workstations for pharmaceutical applications

SYSTAG designs systems for chemical research, process development and scale-up applications and specialises in thermal process safety analysis.

The company offers FlexyCUBE and FlexyPAT, which helps in the research, optimisation and manufacture of fine chemicals and active pharmaceutical ingredients (APIs) for synthetic process development.

Modular and integrated automation solutions are provided for millilitre scale and small-batch production.

SYSTAG provides automated laboratory reactors for the pharmaceutical industry.
The FlexyCUBE parallel synthesis workstation has two reactor units and an overhead stirrer. Each reactor unit has two gravimetric dosages mounted, which includes balances. Up to six units can run on one PC.
The FlexyPAT controlled lab reactor is based on a 1l glass-jacketed reactor with a diaphragm pump and balance for gravimetric feed, as well as one volumetric feed.
Calo2310pro is a heat flow and heat balance calorimeter with a conical triple-jacketed reaction vessel, which is vacuum-insulated and a temperature-controlled reactor lid.
The FlexySys all-in-one software platform has a main screen for a parallel synthesis workstation with synoptics for four reactor units.

The FlexyCUBE parallel synthesis workstation enables processes to be developed efficiently, allowing rapid and robust scale-up and in-depth quality risk analyses.

SYSTAG uses standardised processes to cut costs from early development stages to deliver a high level of reproducibility and informative analyses through an integrated logging function.

Pressure reactors for hydrogenation and catalyst screening

SYSTAG’s controlled lab reactors, including FlexyPAT and FlexyPlant, combine modular, flexible process automation technologies with customised complete solutions for process research or scale-up in the kilo lab.

FlexyPAT and FlexyPlant meet changing requirements and integrate existing peripherals, as well as analytical technologies such as fourier transform infrared (FT-IR) and particle size analysers.

The FlexyPAT automated lab reactor can be used in morphology, process analysis, thermal and physical process technology.

SYSTAG offers 100ml glass-jacketed reactors and pressure reactors with several litres of capacity for pressurised applications such as hydrogenation, polymer research and catalyst screening.

Reaction calorimetry for thermal process safety

SYSTAG’s Calo2310pro reaction calorimeter is used to study synthetic reactions. The FlexyTSC adiabatic safety calorimeter classifies adverse reactions and the thermal potential of a reaction.

Combining thermal parameters such as the power and heat of the reaction, adiabatic temperature rise, maximum temperature for synthesis reaction (MTSR) and heat of decomposition helps to devise individual runaway scenarios.

SYSTAG’s reaction calorimeter and thermal analysis equipment can help to eliminate thermally uncontrolled incidents and associated events.

All SYSTAG solutions have a reaction calorimetry function, including parallel synthesis workstations and controlled lab reactors, which can be retrofitted.

The FlexySys all-in-one software platform is a software application for the management of reactions of various sizes, ranging from millilitre scale to pilot plant applications.

The platform eliminates the process of having to learn several different application platforms, and guarantees quick scale-up and scale-down processes.

FlexySys has an intuitive synoptic system and comprehensive documentation to ensure all information is recorded. The software includes predefined standard operating procedures (SOPs) for controlled lab reactors and parallel synthesis workstations, as well as reaction calorimeters and thermal analysis applications.

The software can be used for up to six experiments in parallel and remains autonomous.

About SYSTAG

Switzerland-based SYSTAG is a global company specialising in automation solutions for the pharmaceutical industry since 1965.

The company offers development, piloting and process control technology, as well as conceptual solutions for process optimisation and safety.